Description

5-Bromo-6-Fluoroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial advanced intermediate in modern organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality building blocks for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting kinases and other enzymes.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive heterocyclic core.
• Material Science Precursor: Serves as a starting material for creating specialized ligands, organic semiconductors, and fluorescent dyes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthesis projects.

Basic Information

Product Name	5-Bromo-6-Fluoroisoquinoline
CAS No.	1239463-43-4
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	Isoquinoline, 5-bromo-6-fluoro-; 6-Fluoro-5-bromoisoquinoline; 5-Bromo-6-fluoro-isoquinoline; 5-Bromo-6-fluoroisoquinoline; 1239463-43-4; 5-Br-6-F-Isoquinoline
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Fluoroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our commitment to reliable supply and batch-to-batch consistency supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.