Description

Isoquinolin-6-Ylboronic Acid Hydrochloride (Pentahydrate) is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex organic molecules. Its defined structure and reactivity make it a reliable reagent for constructing isoquinoline-containing scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs) containing the isoquinoline moiety.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid partner for coupling with aryl/heteroaryl halides to create biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides requiring specific isoquinoline-based architectures.
• Material Science Research: Employed in the synthesis of organic ligands for catalysis and advanced organic electronic materials.
• Chemical Biology & Medicinal Chemistry: Facilitates the creation of chemical probes and library compounds for drug discovery and target identification.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical and CDMO (Contract Development and Manufacturing Organization) services.

Basic Information

Product Name	Isoquinolin-6-Ylboronic Acid Hydrochloride (Pentahydrate)
CAS No.	1236031-63-2
Molecular Formula	C₉H₉BClNO₆ • xH₂O (Pentahydrate)
Molecular Weight	Contact for details
Synonyms	6-Isoquinolineboronic Acid Hydrochloride Pentahydrate; (6-Isoquinolyl)boronic Acid Hydrochloride Hydrate; B-(6-Isoquinolinyl)boronic Acid Hydrochloride; Isoquinoline-6-boronic Acid HCl Salt; 6-Boronoisoquinoline Hydrochloride; 1236031-63-2; Isoquinolin-6-yl-B(OH)₂ • HCl • 5H₂O
EINECS	Contact for details

Quality Control

Every batch of Isoquinolin-6-Ylboronic Acid Hydrochloride (Pentahydrate) is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and assay is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Purity (HPLC)	≥97.0%
Water Content (KF)	Consistent with pentahydrate
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.