Description

(1S)-2-Bromo-1-(4-Fluorophenyl)Ethanol CAS NO 1234372-12-3 is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functional groups make it a critical precursor for constructing complex molecules with precise three-dimensional architecture. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and Contract Research: Essential for methodological studies in organic chemistry, particularly in stereoselective bromination and fluorophenyl chemistry.
• Material Science Research: Potential building block for specialty polymers and liquid crystals due to its fluorinated aromatic structure.

Basic Information

Product Name	(1S)-2-Bromo-1-(4-Fluorophenyl)Ethanol
CAS No.	1234372-12-3
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	(S)-2-Bromo-1-(4-fluorophenyl)ethanol; (1S)-2-Bromo-1-(4-fluorophenyl)ethan-1-ol; (S)-(-)-2-Bromo-1-(4-fluorophenyl)ethanol; 1-(4-Fluorophenyl)-2-bromoethan-1-ol (S)-enantiomer; 4-Fluoro-α-(bromomethyl)benzyl alcohol (S)-form; (S)-1-(4-Fluorophenyl)-2-bromoethanol; (S)-p-Fluoro-α-(bromomethyl)benzyl alcohol
EINECS	Contact for details

Quality Control

Our (1S)-2-Bromo-1-(4-Fluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.