Description

5-Amino-1-(3,5-Difluorophenyl)-1H-Pyrazole-4-Carbonitrile is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemical active ingredients, offering a versatile scaffold for further chemical elaboration. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anti-cancer agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used as a core building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential precursor for the synthesis of specialized polymers, ligands for catalysis, or organic electronic materials.
• Contract Manufacturing (CMO/CDMO): Supplied to custom synthesis organizations for the production of client-specific advanced intermediates.

Basic Information

Product Name	5-Amino-1-(3,5-Difluorophenyl)-1H-Pyrazole-4-Carbonitrile
CAS No.	1232780-81-2
Molecular Formula	C10H5F2N5
Molecular Weight	233.18 g/mol
Synonyms	5-Amino-1-(3,5-difluorophenyl)-1H-pyrazole-4-carbonitrile; 1-(3,5-Difluorophenyl)-5-amino-1H-pyrazole-4-carbonitrile; 5-Amino-1-(3,5-difluorophenyl)-4-cyanopyrazole; 4-Cyano-1-(3,5-difluorophenyl)-1H-pyrazol-5-amine; 1232780-81-2; 5-Amino-1-(3,5-difluorophenyl)pyrazole-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Amino-1-(3,5-Difluorophenyl)-1H-Pyrazole-4-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) with detailed specifications are provided for each lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.