Description

2-(Methylamino-D3)-3',4'-(Methylenedioxy)Butyrophenone is a deuterated analog of a key chemical scaffold, offering enhanced metabolic stability and traceability for advanced research and development. This compound is critical for applications requiring precise isotopic labeling, such as in the synthesis of internal standards for analytical chemistry and the development of novel pharmaceutical agents. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in drug discovery, metabolism studies, and high-precision quantitative analysis.

Application

• Pharmaceutical Research & Development: Serves as a deuterium-labeled intermediate or building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly for pharmacokinetic and metabolic stability studies.
• Analytical Chemistry Standards: Used as a high-purity internal standard or reference material in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification and method validation.
• Isotope Labeling Studies: Enables mechanistic studies in organic chemistry and biochemistry by tracing reaction pathways and metabolic fate due to the deuterium (D) atoms.
• Neurochemical Research: Acts as a precursor or analog in the research of compounds targeting neurological pathways, given the butyrophenone core structure.
• Process Chemistry Development: Employed in the development and scaling of synthetic routes where isotopic labeling is required for patent protection or regulatory filings.

Basic Information

Product Name	2-(Methylamino-D3)-3',4'-(Methylenedioxy)Butyrophenone
CAS No.	1231710-63-6
Molecular Formula	C12H12D3NO3
Molecular Weight	222.27 g/mol
Synonyms	2-[(Methyl-d3)amino]-1-(1,3-benzodioxol-5-yl)butan-1-one; 1-(Benzo[d][1,3]dioxol-5-yl)-2-((methyl-d3)amino)butan-1-one; Deuterated Methylene Dioxy Butyrophenone; 2-(N-Methyl-d3-amino)-3,4-methylenedioxybutyrophenone; 2-(Methyl-d3-amino)-1-(3,4-methylenedioxyphenyl)-1-butanone; MD-D3 Butyrophenone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC), with specifications tailored to research and development requirements. Certificates of Analysis (COA) detailing identity, purity (by HPLC or NMR), and isotopic enrichment are available upon request. Quality is managed under a cGMP-compliant quality system for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Enrichment (D3)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.