Description

5-Methyl-2-[(2-Nitrophenyl)Amino]-3-Thiophenecarboxylic Acid is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides with unique modes of action.
• Material Science: Serves as a building block for organic semiconductors, dyes, or pigments due to its conjugated thiophene and nitroaniline structure.
• Academic & Contract Research: Employed in universities and CROs for methodological studies and the discovery of new chemical entities.
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions and other transformations to create complex heterocyclic systems.

Basic Information

Product Name	5-Methyl-2-[(2-Nitrophenyl)Amino]-3-Thiophenecarboxylic Acid
CAS No.	1231161-31-1
Molecular Formula	C13H10N2O4S
Molecular Weight	290.30 g/mol
Synonyms	3-Thiophenecarboxylic acid, 5-methyl-2-[(2-nitrophenyl)amino]-; 2-((2-Nitrophenyl)amino)-5-methylthiophene-3-carboxylic acid; 5-Methyl-2-(2-nitroanilino)thiophene-3-carboxylic acid; 2-Amino-5-methyl-3-thiophenecarboxylic acid 2-nitrophenyl derivative; N-(2-Nitrophenyl)-5-methyl-3-thiophenecarboxamide precursor
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-[(2-Nitrophenyl)Amino]-3-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.