Description

(2-Fluoro-4-Methylbenzyl)Triphenylphosphonium Bromide (Wxc06852) is a high-purity, organophosphorus salt widely used as a key reagent in advanced organic synthesis. Its primary value lies in its role as a stable Wittig reagent or ylide precursor, enabling the efficient construction of complex olefins and pharmaceutical intermediates. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for complex molecule synthesis.

Application

• Wittig Olefination Reactions: As a crucial phosphonium salt for generating stabilized ylides to synthesize substituted alkenes with high stereoselectivity.
• Pharmaceutical Intermediate Synthesis: For constructing fluorinated and methyl-substituted aromatic scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Active Ingredient Development: Used in the synthesis of novel herbicides, fungicides, and insecticides containing fluorinated aromatic systems.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized phosphine ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals where specific fluorine substitution patterns are required.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(2-Fluoro-4-Methylbenzyl)Triphenylphosphonium Bromide (Wxc06852)
CAS No.	1228763-43-6
Molecular Formula	C26H23BrFP
Molecular Weight	456.34 g/mol
Synonyms	(2-Fluoro-4-methylbenzyl)triphenylphosphonium bromide; (2-Fluoro-p-tolylmethyl)triphenylphosphonium bromide; [(2-Fluoro-4-methylphenyl)methyl]triphenylphosphonium bromide; Triphenyl(2-fluoro-4-methylbenzyl)phosphonium bromide; WXC06852; Phosphonium, (2-fluoro-4-methylbenzyl)triphenyl-, bromide; (α-Fluoro-α-methyl-m-tolyl)triphenylphosphonium bromide (related isomer)
EINECS	Contact for details

Quality Control

Every batch of (2-Fluoro-4-Methylbenzyl)Triphenylphosphonium Bromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay (by HPLC/NMR), identity confirmation, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.