Description

2-Fluoro-3-(Piperidin-1-Ylmethyl)Phenylboronic Acid CAS NO 1228594-52-2 is a sophisticated boronic acid derivative featuring a fluorinated phenyl ring and a piperidinylmethyl substituent. This compound is a critical high-purity building block in modern synthetic chemistry, valued for its role in facilitating key carbon-carbon bond formation reactions. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology: Employed in the synthesis of molecular probes and bioconjugates for studying biological pathways and protein interactions.
• Catalyst Ligand Synthesis: Utilized to construct complex ligand frameworks for transition metal catalysts used in asymmetric synthesis.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Product Name	2-Fluoro-3-(Piperidin-1-Ylmethyl)Phenylboronic Acid
CAS No.	1228594-52-2
Molecular Formula	C₁₃H₁₉BFNO₂
Molecular Weight	251.11 g/mol
Synonyms	[2-Fluoro-3-(piperidin-1-ylmethyl)phenyl]boronic acid; 2-Fluoro-3-(1-piperidinylmethyl)benzeneboronic Acid; (2-Fluoro-3-((piperidin-1-yl)methyl)phenyl)boronic Acid; Boronic acid, B-[2-fluoro-3-[(1-piperidinyl)methyl]phenyl]-; 2-Fluoro-3-(piperidin-1-ylmethyl)benzeneboronic Acid; 1228594-52-2; B-(2-Fluoro-3-(piperidin-1-ylmethyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-(Piperidin-1-Ylmethyl)Phenylboronic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.