Description

(1R)-1-Aminoindan-5-Ol CAS NO 1228571-48-9 is a chiral aminoindanol derivative, a high-purity building block of significant interest in advanced organic synthesis. Its enantiomerically pure structure makes it a valuable intermediate for creating complex, biologically active molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in asymmetric synthesis and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Fine Chemical Synthesis: Serves as a building block for complex natural products, agrochemicals, and specialty chemicals requiring high stereochemical purity.
• Academic & Industrial Research: A valuable tool compound in medicinal chemistry and process chemistry for studying structure-activity relationships (SAR).
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(1R)-1-Aminoindan-5-Ol
CAS No.	1228571-48-9
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(1R)-1-Amino-5-hydroxyindane; (1R)-5-Hydroxy-1-aminoindane; (R)-1-Aminoindan-5-ol; (R)-5-Hydroxy-1-aminoindane; (1R,2S)-rel-1-Amino-2,3-dihydro-1H-inden-5-ol; 1H-Inden-5-ol, 1-amino-2,3-dihydro-, (1R)-; (R)-1-Amino-2,3-dihydro-1H-inden-5-ol
EINECS	Contact for details

Quality Control

Our (1R)-1-Aminoindan-5-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.