Description

tert-Butyl [2-(5-Chloro-1H-Indol-3-Yl)Ethyl]-Carbamate is a high-purity, protected indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• API Development: Used as a protected synthon for constructing indole-based active pharmaceutical ingredients.
• Medicinal Chemistry Research: Serves as a versatile building block in structure-activity relationship (SAR) studies and lead optimization.
• Peptidomimetic Synthesis: Employed in the creation of peptide-like molecules where the indole-carbamate structure is integral to biological activity.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and receptor interactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.

Basic Information

Product Name	tert-Butyl [2-(5-Chloro-1H-Indol-3-Yl)Ethyl]-Carbamate
CAS No.	1228552-16-6
Molecular Formula	C15H19ClN2O2
Molecular Weight	294.78 g/mol
Synonyms	Boc-5-Chlorotryptamine; N-Boc-5-Chlorotryptamine; tert-Butyl (2-(5-Chloro-1H-indol-3-yl)ethyl)carbamate; 5-Chloro-N-(tert-butoxycarbonyl)tryptamine; 2-(5-Chloro-1H-indol-3-yl)ethyl-carbamic acid tert-butyl ester; 1,1-Dimethylethyl N-[2-(5-chloro-1H-indol-3-yl)ethyl]carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl [2-(5-Chloro-1H-Indol-3-Yl)Ethyl]-Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.