Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 5-Bromo-2-Methyl-, Methyl Ester is a high-purity, synthetically valuable heterocyclic building block. This compound is essential for medicinal chemistry research and development, serving as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and advanced material scientists seeking to incorporate its unique fused pyrrolopyridine scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Development: Serves as a precursor in the creation of novel pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Organic Electronic Materials: Potential precursor for the development of advanced organic semiconductors and light-emitting materials due to its conjugated system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and development projects.

Basic Information

Item	Details
Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 5-Bromo-2-Methyl-, Methyl Ester
CAS No.	1228551-75-4
Molecular Formula	C10H9BrN2O2
Molecular Weight	269.10 g/mol
Synonyms	5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester; Methyl 5-bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylate; 5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester; 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-bromo-2-methyl-, methyl ester; 1228551-75-4; 5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester; 5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 5-Bromo-2-Methyl-, Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.