Description

5-Bromo-1-Pyrimidin-2-Yl-1H-Indol is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated structure.
• Chemical Biology: Employed as a molecular probe or tag in bioconjugation and proteomics research to study biological processes.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploring new chemical spaces in heterocyclic chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals and advanced intermediates.

Basic Information

Product Name	5-Bromo-1-Pyrimidin-2-Yl-1H-Indol
CAS No.	1228147-70-3
Molecular Formula	C12H7BrN4
Molecular Weight	287.11 g/mol
Synonyms	5-Bromo-1-(pyrimidin-2-yl)-1H-indole; 1H-Indole, 5-bromo-1-(2-pyrimidinyl)-; 5-Bromo-1-(2-pyrimidinyl)indole; 5-Bromo-1-pyrimidin-2-ylindole; 1228147-70-3; 5-Bromo-1-(pyrimidin-2-yl)indole
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Pyrimidin-2-Yl-1H-Indol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.