Description

(2-Amino-6-Bromo-3-Fluorophenyl)Methanol is a high-purity, multi-functional aromatic building block featuring amino, bromo, fluoro, and hydroxymethyl substituents. This unique combination of functional groups makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to its reactive amino and bromo groups for further derivatization.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	(2-Amino-6-Bromo-3-Fluorophenyl)Methanol
CAS No.	1227958-14-6
Molecular Formula	C7H7BrFNO
Molecular Weight	220.04 g/mol
Synonyms	2-Amino-6-bromo-3-fluorobenzyl alcohol; (2-Amino-6-bromo-3-fluorophenyl)methanol; 1-(Aminomethyl)-2-bromo-5-fluorophenol (tautomer); 6-Bromo-3-fluoro-2-aminobenzyl alcohol; 2-(Hydroxymethyl)-3-bromo-6-fluoroaniline; Benzenemethanol, 2-amino-6-bromo-3-fluoro-; CAS 1227958-14-6
EINECS	Contact for details

Quality Control

Our (2-Amino-6-Bromo-3-Fluorophenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.