Description

8-Bromo-5,5,7,7-Tetramethyl-4-Nitro-1,5,6,7-Tetrahydrocyclopenta[F]Indazole is a high-purity, advanced pharmaceutical intermediate characterized by its complex, functionalized heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and inflammation research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile bromo and nitro functional groups.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study biological pathways and protein functions.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses, leveraging its reactivity for further functionalization, such as cross-coupling reactions.
• Agrochemical Research: Potential intermediate in the research and development of new active ingredients for crop protection.
• Academic Research: Utilized in universities and research institutes for methodological development and exploring new chemical spaces.

Basic Information

Item	Details
Product Name	8-Bromo-5,5,7,7-Tetramethyl-4-Nitro-1,5,6,7-Tetrahydrocyclopenta[F]Indazole
CAS No.	1227955-14-7
Molecular Formula	C₁₄H₁₆BrN₃O₂
Molecular Weight	338.20 g/mol
Synonyms	8-Bromo-5,5,7,7-tetramethyl-4-nitro-1,5,6,7-tetrahydro-2H-cyclopenta[f]indazole; 8-Bromo-5,5,7,7-tetramethyl-4-nitro-2,5,6,7-tetrahydro-1H-cyclopenta[f]indazole; 1227955-14-7; 8-Bromo-4-nitro-5,5,7,7-tetramethyl-1,5,6,7-tetrahydrocyclopenta[f]indazole; Cyclopenta[f]indazole, 8-bromo-5,5,7,7-tetramethyl-4-nitro-1,5,6,7-tetrahydro-
EINECS	Contact for details

Quality Control

Our 8-Bromo-5,5,7,7-Tetramethyl-4-Nitro-1,5,6,7-Tetrahydrocyclopenta[F]Indazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.