Description

Ethyl 6-Bromo-3-(1H-Pyrrol-1-Yl)-1-Benzothiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzothiophene core functionalized with bromo and pyrrolyl substituents. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new active ingredients in crop protection and pest management products.
• Material Science Precursor: Potential use in the development of organic electronic materials due to the conjugated benzothiophene system.
• Chemical Biology Probe: Can be utilized to develop molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of client-specific molecules.

Basic Information

Product Name	Ethyl 6-Bromo-3-(1H-Pyrrol-1-Yl)-1-Benzothiophene-2-Carboxylate
CAS No.	1227955-06-7
Molecular Formula	C15H12BrNO2S
Molecular Weight	350.23 g/mol
Synonyms	6-Bromo-3-(1H-pyrrol-1-yl)-1-benzothiophene-2-carboxylic acid ethyl ester; Ethyl 6-bromo-3-pyrrol-1-yl-1-benzothiophene-2-carboxylate; 1-Benzothiophene-2-carboxylic acid, 6-bromo-3-(1H-pyrrol-1-yl)-, ethyl ester; 1227955-06-7; 6-Bromo-3-(pyrrol-1-yl)benzo[b]thiophene-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromo-3-(1H-Pyrrol-1-Yl)-1-Benzothiophene-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development toward cGMP (current Good Manufacturing Practice) requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.