Description

4-{2-[5-(Trifluoromethyl)-1H-Pyrazol-1-Yl]-1,3-Thiazol-4-Yl}Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating pyrazole and thiazole rings. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its trifluoromethyl and nitrile functional groups for bioactivity.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique electronic or optical properties.
• Chemical Biology: Employed as a molecular probe or tag in biochemical assays due to its distinct structural features.
• Organic Synthesis Building Block: Provides a versatile scaffold for further functionalization in complex multi-step synthetic routes.

Basic Information

Product Name	4-{2-[5-(Trifluoromethyl)-1H-Pyrazol-1-Yl]-1,3-Thiazol-4-Yl}Benzonitrile
CAS No.	1227954-96-2
Molecular Formula	C14H7F3N4S
Molecular Weight	320.29 g/mol
Synonyms	4-[2-[5-(Trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl]benzonitrile; 4-(2-(5-(Trifluoromethyl)-1H-pyrazol-1-yl)thiazol-4-yl)benzonitrile; 1227954-96-2; 4-[2-[5-(Trifluoromethyl)pyrazol-1-yl]-1,3-thiazol-4-yl]benzonitrile; Benzonitrile, 4-[2-[5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl]-
EINECS	Contact for details

Quality Control

Our production of 4-{2-[5-(Trifluoromethyl)-1H-Pyrazol-1-Yl]-1,3-Thiazol-4-Yl}Benzonitrile adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.