Description

4-Bromo-6-(Trifluoromethyl)Isoquinolin-1(2H)-One is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is essential for medicinal chemistry and materials science research, offering a unique trifluoromethyl and bromo-substituted isoquinolinone scaffold. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection products.
• Material Science: Serves as a precursor for organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research and assay development.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and exploration of novel heterocyclic chemistry in academic and CRO laboratories.

Basic Information

Product Name	4-Bromo-6-(Trifluoromethyl)Isoquinolin-1(2H)-One
CAS No.	1227608-00-5
Molecular Formula	C10H5BrF3NO
Molecular Weight	292.06 g/mol
Synonyms	4-Bromo-6-(trifluoromethyl)-1,2-dihydroisoquinolin-1-one; 4-Bromo-6-(trifluoromethyl)-2H-isoquinolin-1-one; 1(2H)-Isoquinolinone, 4-bromo-6-(trifluoromethyl)-; 4-Bromo-6-trifluoromethylisoquinolin-1(2H)-one; 1227608-00-5; 4-Bromo-6-(trifluoromethyl)isoquinolin-1-ol (tautomer)
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-(Trifluoromethyl)Isoquinolin-1(2H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global B2B partners in the pharmaceutical and fine chemical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.