Description

7-Chloro-6-Hydroxy-1H-Indole-3-Carbaldehyde is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and hydroxylated structure makes it a versatile intermediate for constructing complex molecules with tailored biological and chemical properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for developing kinase inhibitors, receptor modulators, and other biologically active heterocyclic compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold's bioactivity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers, dyes, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in the study of protein interactions and enzymatic activity due to its reactive aldehyde group.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways in university and CRO laboratories.

Basic Information

Item	Details
Product Name	7-Chloro-6-Hydroxy-1H-Indole-3-Carbaldehyde
CAS No.	1227575-94-1
Molecular Formula	C9H6ClNO2
Molecular Weight	195.60 g/mol
Synonyms	7-Chloro-6-hydroxyindole-3-carboxaldehyde; 3-Formyl-7-chloro-6-hydroxyindole; 7-Chloro-6-hydroxy-1H-indole-3-carboxaldehyde; 1H-Indole-3-carboxaldehyde, 7-chloro-6-hydroxy-; 7-Chloro-6-hydroxyindole-3-carbaldehyde; 7-Chloro-6-hydroxy-3-formylindole
EINECS	Contact for details

Quality Control

Every batch of 7-Chloro-6-Hydroxy-1H-Indole-3-Carbaldehyde is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.