Description

4-Chloromethyl-3-(Trifluoromethyl)Pyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive chloromethyl group and a stable trifluoromethyl moiety, makes it indispensable for introducing specific functionalities into target molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used to construct advanced pyridine-based herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of novel organic electronic materials and liquid crystals due to its unique electronic properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on client-specific molecular scaffolds.

Basic Information

Product Name	4-Chloromethyl-3-(Trifluoromethyl)Pyridine
CAS No.	1227574-95-9
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	3-(Trifluoromethyl)-4-pyridinemethanol, chloride; 4-(Chloromethyl)-3-(trifluoromethyl)pyridine; 3-Trifluoromethyl-4-chloromethylpyridine; 4-Pyridinemethanol, 3-(trifluoromethyl)-, chloride; 4-Chloromethyl-3-trifluoromethylpyridine; 3-(Trifluoromethyl)-4-chloromethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Chloromethyl-3-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment. Our quality protocols are designed to support applications requiring material consistency under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.