Description

3-(Bromomethyl)Tetrahydro-2H-Thiopyran 1,1-Dioxide (Saltdata: Free) is a high-purity, functionalized sulfone building block of significant interest in advanced organic synthesis. Its core value lies in the reactive bromomethyl group attached to a conformationally constrained, oxidized thiopyran ring, making it a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, linker development, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in fragment-based drug discovery and for introducing sulfone-containing pharmacophores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require sulfone functionalities.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with specific thermal or chemical resistance properties.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes (ABPs) and bioconjugation reagents that target specific enzymes or biomolecules.
• Ligand & Catalyst Development: Useful precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring this specialized brominated sulfone scaffold.

Basic Information

Product Name	3-(Bromomethyl)Tetrahydro-2H-Thiopyran 1,1-Dioxide (Saltdata: Free)
CAS No.	1227465-51-1
Molecular Formula	C6H11BrO2S
Molecular Weight	227.12 g/mol
Synonyms	3-(Bromomethyl)tetrahydro-2H-thiopyran 1,1-dioxide; Tetrahydro-2H-thiopyran-3-ylmethanol, 1,1-dioxide, 3-(bromomethyl)-; 3-(Bromomethyl)thiane 1,1-dioxide; Bromomethyl tetrahydrothiopyran dioxide; (Oxidized Thiopyran Bromomethyl Derivative); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 3-(Bromomethyl)Tetrahydro-2H-Thiopyran 1,1-Dioxide is produced and analyzed under strict quality management protocols to ensure consistency and reliability for research and development purposes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.