Description

1-(Phenylsulphonyl)-2-Bromo-7-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated and sulfonylated azaindole structure. This compound is of significant value for its role as a versatile building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel small-molecule therapeutics, particularly in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its reactive bromine and sulfonyl functional groups.
• Organic Synthesis: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization to create diverse chemical libraries.
• Biochemical Probe Development: Utilized in the design and creation of chemical probes for studying biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for clinical trials.

Basic Information

Product Name	1-(Phenylsulphonyl)-2-Bromo-7-Azaindole
CAS No.	1227271-03-5
Molecular Formula	C₁₃H₉BrN₂O₂S
Molecular Weight	337.19 g/mol
Synonyms	2-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 2-Bromo-1-(benzenesulfonyl)-7-azaindole; 2-Bromo-1-(phenylsulfonyl)-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 2-bromo-1-(phenylsulfonyl)-; 1-(Phenylsulfonyl)-2-bromo-1H-pyrrolo[2,3-b]pyridine; 2-Bromo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our production of 1-(Phenylsulphonyl)-2-Bromo-7-Azaindole adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.