Description

1-(Phenylsulphonyl)-6-Bromo-2-Iodo-5-Methoxy-7-Azaindole is a high-purity, multi-halogenated azaindole derivative designed for advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate, offering versatile reactivity for constructing complex heterocyclic scaffolds. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for lead optimization and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead compound optimization due to its reactive halogen sites.
• Agrochemical Development: Intermediate in the research and synthesis of novel herbicides and fungicides.
• Chemical Biology Probes: Serves as a precursor for labeled compounds used in biochemical assay development and target identification.
• Custom Synthesis: Starting material for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds.
• Academic Research: Used in university and institutional labs for methodological development in heterocyclic and organohalogen chemistry.

Basic Information

Product Name	1-(Phenylsulphonyl)-6-Bromo-2-Iodo-5-Methoxy-7-Azaindole
CAS No.	1227270-99-6
Molecular Formula	C14H10BrIN2O3S
Molecular Weight	492.11 g/mol
Synonyms	6-Bromo-2-iodo-5-methoxy-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-bromo-2-iodo-5-methoxy-1-(phenylsulfonyl)-; 6-Bromo-2-iodo-5-methoxy-1-(benzenesulfonyl)-7-azaindole; 1-(Phenylsulfonyl)-6-bromo-2-iodo-5-methoxy-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 1-(phenylsulfonyl)-6-bromo-2-iodo-5-methoxy-; 6-Bromo-2-iodo-5-methoxy-1-(phenylsulfonyl)-7-azaindole
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-6-Bromo-2-Iodo-5-Methoxy-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.