Description

1-Benzyl-3-Iodo-4-Hydroxy-7-Azaindole is a high-purity, functionalized azaindole derivative, a crucial scaffold in modern medicinal chemistry and pharmaceutical research. Its value lies in its unique halogenated and hydroxylated structure, making it a versatile and valuable advanced pharmaceutical intermediate for the synthesis of targeted bioactive molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for developing new drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its modifiable benzyl, iodo, and hydroxy functional groups.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds or affinity probes to study enzyme function and protein interactions.
• Agrochemical Synthesis: Potential intermediate in the research and development of novel herbicides or plant growth regulators.
• Material Science Research: Exploration of its use in the synthesis of organic electronic materials or metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development projects for global clients.

Basic Information

Item	Detail
Product Name	1-Benzyl-3-Iodo-4-Hydroxy-7-Azaindole
CAS No.	1227270-98-5
Molecular Formula	C14H11IN2O
Molecular Weight	350.16 g/mol
Synonyms	4-Hydroxy-1-benzyl-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-1-benzyl-4-hydroxy-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 1-benzyl-3-iodo-4-hydroxy-; 1-Benzyl-3-iodo-4-hydroxy-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 1-benzyl-3-iodo-4-hydroxy-; BIA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-Benzyl-3-Iodo-4-Hydroxy-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.