Description

1-(Phenylsulfonyl)-3-Nitro-2-Iodo-5-Azaindole is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is particularly significant for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique sulfonyl, nitro, and iodo substituents enable complex molecular transformations. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex azaindole-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active molecules targeting the azaindole core.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the azaindole structure for enhanced activity.
• Material Science Precursor: Serves as a specialized monomer or precursor for creating organic electronic materials and advanced polymers with specific optoelectronic properties.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways due to its reactive halogen and electron-withdrawing groups.
• Academic & Contract Research: Essential for methodological research in organic synthesis, including cross-coupling reactions and heterocyclic chemistry studies.

Basic Information

Product Name	1-(Phenylsulfonyl)-3-Nitro-2-Iodo-5-Azaindole
CAS No.	1227270-94-1
Molecular Formula	C13H8IN3O4S
Molecular Weight	429.19 g/mol
Synonyms	1-(Benzenesulfonyl)-3-nitro-2-iodo-1H-pyrrolo[2,3-b]pyridine; 2-Iodo-3-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 3-Nitro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 2-iodo-3-nitro-1-(phenylsulfonyl)-; 5-Azaindole, 1-(phenylsulfonyl)-3-nitro-2-iodo-; 1227270-94-1
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-3-Nitro-2-Iodo-5-Azaindole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.