Description

3-Iodo-4-Benzyloxy-7-Azaindole is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of kinase inhibitors and other biologically active molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probes: Used in the development of tool compounds for studying enzyme function and cellular signaling pathways.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce the complex 7-azaindole moiety.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process scale-up.
• Academic Research: Utilized in university and institutional labs for novel heterocyclic chemistry and drug discovery projects.

Basic Information

Product Name	3-Iodo-4-Benzyloxy-7-Azaindole
CAS No.	1227270-65-6
Molecular Formula	C16H13IN2O
Molecular Weight	376.19 g/mol
Synonyms	4-(Benzyloxy)-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-4-(phenylmethoxy)-1H-pyrrolo[2,3-b]pyridine; 4-Benzyloxy-3-iodo-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 4-(benzyloxy)-3-iodo-; 3-Iodo-4-benzyloxy-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-Benzyloxy-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.