Description

5,7-Dichloro-1-(Phenylsulfonyl)-6-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique azaindole core functionalized with chloro and phenylsulfonyl groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitor programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore novel chemical space.
• Biochemical Tool Compound: Serves as a reference standard or a precursor for probes in biological assay development and target validation.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses due to its reactive halogen and sulfonyl functional groups.

Basic Information

Product Name	5,7-Dichloro-1-(Phenylsulfonyl)-6-Azaindole
CAS No.	1227270-60-1
Molecular Formula	C13H8Cl2N2O2S
Molecular Weight	339.18 g/mol
Synonyms	1-(Benzenesulfonyl)-5,7-dichloro-1H-pyrrolo[2,3-b]pyridine; 5,7-Dichloro-1H-pyrrolo[2,3-b]pyridine 1-(phenylsulfonyl); 5,7-Dichloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5,7-dichloro-1-(phenylsulfonyl)-; 5,7-Dichloro-1-(benzenesulfonyl)-6-azaindole
EINECS	Contact for details

Quality Control

Our 5,7-Dichloro-1-(Phenylsulfonyl)-6-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.