Description

1-(Phenylsulphonyl)-2,5-Dimethyl-7-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. Its core value lies in its role as a critical building block for the synthesis of novel, small-molecule drug candidates, particularly in oncology and other therapeutic areas. This compound is essential for research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other biologically active molecules.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• Process Chemistry Development: Serves as a starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Potential use as a probe or tool compound in biochemical assays to study specific enzyme pathways.

Basic Information

Product Name	1-(Phenylsulphonyl)-2,5-Dimethyl-7-Azaindole
CAS No.	1227270-58-7
Molecular Formula	C17H16N2O2S
Molecular Weight	312.39 g/mol
Synonyms	1-(Benzenesulfonyl)-2,5-dimethyl-1H-pyrrolo[2,3-b]pyridine; 2,5-Dimethyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 2,5-dimethyl-1-(phenylsulfonyl)-; 7-Azaindole, 1-(phenylsulfonyl)-2,5-dimethyl-; 2,5-Dimethyl-7-azaindole-1-sulfonylbenzene
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-2,5-Dimethyl-7-Azaindole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.