Description

1-(Phenylsulfonyl)-6-Bromo-5-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonyl and bromo-substituted azaindole scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors, oncology treatments, and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drugs, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile functional groups.
• Oncology Drug Discovery: Serves as a core scaffold for compounds targeting specific cancer pathways and protein kinases.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and cellular signaling mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Product Name	1-(Phenylsulfonyl)-6-Bromo-5-Azaindole
CAS No.	1227270-56-5
Molecular Formula	C₁₃H₉BrN₂O₂S
Molecular Weight	337.19 g/mol
Synonyms	6-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 6-Bromo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-bromo-1-(phenylsulfonyl)-; 6-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Phenylsulfonyl)-6-bromo-1H-pyrrolo[2,3-b]pyridine; 6-Bromo-1-(benzenesulfonyl)-1H-7-azaindole; 6-Bromo-1-(phenylsulfonyl)-1H-7-azaindole; 1-Benzenesulfonyl-6-bromo-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-6-Bromo-5-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to guarantee reliable quality and traceability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under inert atmosphere or with appropriate desiccants to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.