Description

1-(Phenylsulphonyl)-6-Methyl-7-Azaindole-2-Carboxylic Acid is a high-value, synthetically derived heterocyclic building block of significant interest in advanced pharmaceutical research and development. Its core value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the synthesis of kinase inhibitors and other targeted therapeutic agents. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to develop novel drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel small-molecule drugs, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical entities.
• Process Chemistry & Scale-up: Serves as a critical building block for the pilot-scale and commercial-scale synthesis of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Potential use in the development of probes for studying biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences sector.

Basic Information

Product Name	1-(Phenylsulphonyl)-6-Methyl-7-Azaindole-2-Carboxylic Acid
CAS No.	1227270-51-0
Molecular Formula	C17H14N2O4S
Molecular Weight	342.37 g/mol
Synonyms	1-(Benzenesulfonyl)-6-methyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 6-Methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 6-methyl-1-(phenylsulfonyl)-; 1-(Phenylsulfonyl)-6-methyl-7-azaindole-2-carboxylic acid; 6-Methyl-1-tosyl-7-azaindole-2-carboxylic acid (common alias); 1-Phenylsulfonyl-6-methyl-7-aza-indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-6-Methyl-7-Azaindole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.