Description

1-(Phenylsulphonyl)-2-Iodo-4-Methyl-7-Azaindole is a high-value, halogenated azaindole derivative featuring a phenylsulfonyl protecting group. This compound matters as a sophisticated pharmaceutical intermediate and organic synthesis building block, prized for its unique reactivity profile that enables the construction of complex heterocyclic scaffolds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery programs and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of targeted kinase inhibitors and other small molecule therapeutics, particularly in oncology and antiviral research.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions due to the reactive iodine moiety.
• Agrochemical Research: Serves as a precursor in developing new active ingredients for crop protection products.
• Chemical Biology Probe Development: Used to create tagged or modified molecules for studying biological pathways and protein interactions.
• Material Science Research: Potential monomer or precursor for constructing organic electronic materials or metal-organic frameworks (MOFs).
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and novel heterocycle synthesis.

Basic Information

Product Name	1-(Phenylsulphonyl)-2-Iodo-4-Methyl-7-Azaindole
CAS No.	1227270-47-4
Molecular Formula	C16H13IN2O2S
Molecular Weight	424.26 g/mol
Synonyms	1-(Phenylsulfonyl)-2-iodo-4-methyl-1H-pyrrolo[2,3-b]pyridine; 2-Iodo-4-methyl-1-(phenylsulfonyl)-7-azaindole; 4-Methyl-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 2-iodo-4-methyl-1-(phenylsulfonyl)-; 1-Benzenesulfonyl-2-iodo-4-methyl-7-azaindole; 2-Iodo-4-methyl-7-azaindole-1-phenylsulfonamide; 1-(Phenylsulfonyl)-2-iodo-4-methyl-7-aza-indole
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-2-Iodo-4-Methyl-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.