Description

1-(Phenylsulphonyl)-4-Cyano-6-Methyl-7-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique azaindole core functionalized with cyano and phenylsulfonyl groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule drugs, where its specific scaffold is valued for modulating biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Probe Development: Serves as a core structure for creating selective probes to study specific enzyme pathways and biological mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for pioneering research in heterocyclic chemistry and drug design.

Basic Information

Product Name	1-(Phenylsulphonyl)-4-Cyano-6-Methyl-7-Azaindole
CAS No.	1227270-24-7
Molecular Formula	C17H11N3O2S
Molecular Weight	321.36 g/mol
Synonyms	1-(Phenylsulfonyl)-4-cyano-6-methyl-1H-pyrrolo[2,3-b]pyridine; 4-Cyano-6-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 6-Methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile, 6-methyl-1-(phenylsulfonyl)-; 7-Azaindole, 1-(phenylsulfonyl)-4-cyano-6-methyl-
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-4-Cyano-6-Methyl-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.