Description

1-(Phenylsulfonyl)-4-Methoxy-5-Azaindole is a high-purity, functionalized azaindole derivative, serving as a critical advanced intermediate in modern pharmaceutical research and development. Its unique sulfonyl and methoxy-substituted heterocyclic structure makes it a valuable scaffold for constructing novel bioactive molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve drug-like properties.
• Chemical Biology Probes: Serves as a core structure for developing selective chemical probes to study enzyme function and cellular signaling processes.
• Agrochemical Development: Potential intermediate in the research and synthesis of new active ingredients for crop protection products.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-(Phenylsulfonyl)-4-Methoxy-5-Azaindole
CAS No.	1227270-22-5
Molecular Formula	C15H12N2O3S
Molecular Weight	300.33 g/mol
Synonyms	4-Methoxy-1-(phenylsulfonyl)-1H-pyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine, 4-methoxy-1-(phenylsulfonyl)-; 4-Methoxy-1-(benzenesulfonyl)-1H-pyrrolo[3,2-c]pyridine; 1-(Phenylsulfonyl)-4-methoxy-1H-pyrrolo[3,2-c]pyridine; 4-Methoxy-1-(phenylsulfonyl)-7-azaindole; 1-Benzenesulfonyl-4-methoxy-5-azaindole
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-4-Methoxy-5-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under anhydrous conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.