Description

1-(Phenylsulphonyl)-6-Bromo-2-Iodo-7-Azaindole is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring bromine and iodine substituents on the 7-azaindole core, makes it a versatile and valuable intermediate for constructing complex pharmacophores. This compound is primarily targeted at pharmaceutical research and development organizations engaged in medicinal chemistry, particularly for the synthesis of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for developing labeled compounds or probes to study biological pathways.
• Heterocyclic Chemistry: Employed in advanced organic synthesis to explore new reactions and create diverse chemical libraries.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.
• Material Science: Can be investigated as a monomer or precursor for functional organic materials.

Basic Information

Product Name	1-(Phenylsulphonyl)-6-Bromo-2-Iodo-7-Azaindole
CAS No.	1227270-17-8
Molecular Formula	C13H8BrIN2O2S
Molecular Weight	462.09 g/mol
Synonyms	6-Bromo-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-bromo-2-iodo-1-(phenylsulfonyl)-; 6-Bromo-2-iodo-1-(benzenesulfonyl)-7-azaindole; 1-(Phenylsulfonyl)-6-bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine; 6-Bromo-2-iodo-1-(phenylsulfonyl)-7-azaindole; 1-(Benzenesulfonyl)-6-bromo-2-iodo-7-azaindole; 1-(Phenylsulfonyl)-6-bromo-2-iodo-7-azaindole; 1227270-17-8
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-6-Bromo-2-Iodo-7-Azaindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.