Description

2-Iodo-5-Methyl-7-Azaindole is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial scaffold in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns for introducing halogen atoms and exploring structure-activity relationships (SAR).
• Agrochemical Development: Acts as a building block for novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Employed in the development of organic electronic materials and photoactive compounds.
• Cross-Coupling Reactions: A valuable substrate for palladium-catalyzed reactions such as Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.

Basic Information

Product Name	2-Iodo-5-Methyl-7-Azaindole
CAS No.	1227270-15-6
Molecular Formula	C8H7IN2
Molecular Weight	258.06 g/mol
Synonyms	5-Methyl-2-iodo-7-azaindole; 2-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 2-iodo-5-methyl-; 5-Methyl-2-iodo-1H-pyrrolo[2,3-b]pyridine; 2-Iodo-5-methyl-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 2-Iodo-5-Methyl-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.