Description

1-(Phenylsulphonyl)-5-Bromo-6-Methyl-7-Azaindole-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block for medicinal chemistry research and development, enabling the synthesis of novel drug candidates. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and antiviral fields.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Used in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), especially kinase inhibitors.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Employed in university and institutional labs for exploratory research in organic and heterocyclic chemistry.

Basic Information

Product Name	1-(Phenylsulphonyl)-5-Bromo-6-Methyl-7-Azaindole-2-Carboxylic Acid
CAS No.	1227269-29-5
Molecular Formula	C17H11BrN2O4S
Molecular Weight	419.25 g/mol
Synonyms	5-Bromo-6-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-bromo-6-methyl-1-(phenylsulfonyl)-; 5-Bromo-6-methyl-1-(phenylsulfonyl)-7-azaindole-2-carboxylic acid; 1-(Phenylsulfonyl)-5-bromo-6-methyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 5-Bromo-6-methyl-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-5-Bromo-6-Methyl-7-Azaindole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.