Description

1-(Phenylsulphonyl)-4-Chloro-6-Methyl-7-Azaindole is a high-value, synthetically derived azaindole derivative featuring a phenylsulfonyl protective group and a chloro substituent. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the development of novel active compounds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for drug discovery and the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used as a building block for developing new active ingredients in crop protection products.
• Organic Synthesis Building Block: The unique 7-azaindole scaffold with sulfonyl and chloro functionalities makes it valuable for constructing complex heterocyclic libraries.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes during drug discovery.
• Chemical Research & Development: Serves as a specialized reagent for methodological development in synthetic organic chemistry.

Basic Information

Product Name	1-(Phenylsulphonyl)-4-Chloro-6-Methyl-7-Azaindole
CAS No.	1227269-27-3
Molecular Formula	C15H11ClN2O2S
Molecular Weight	318.78 g/mol
Synonyms	4-Chloro-6-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine; 1H-Pyrrolo[2,3-c]pyridine, 4-chloro-6-methyl-1-(phenylsulfonyl)-; 4-Chloro-6-methyl-1-(phenylsulfonyl)-7-azaindole; 1-(Phenylsulfonyl)-4-chloro-6-methyl-1H-pyrrolo[2,3-c]pyridine; 4-Chloro-6-methyl-1-(benzenesulfonyl)-1H-pyrrolo[2,3-c]pyridine
EINECS	Contact for details

Quality Control

Our production of 1-(Phenylsulphonyl)-4-Chloro-6-Methyl-7-Azaindole adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.