Description

5-Bromo-1-(Phenylsulfonyl)-6-Azaindole-2-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique azaindole scaffold functionalized with bromo, phenylsulfonyl, and aldehyde groups. This compound matters as a critical building block in medicinal chemistry, enabling the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors, anti-cancer agents, and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex bioactive molecules and potential drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Kinase Inhibitor Development: A valuable scaffold for creating selective inhibitors of various protein kinases.
• Anti-cancer Agent Synthesis: Employed in the construction of molecules designed to interfere with cancer cell proliferation and survival pathways.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke chemical synthesis projects requiring high-fidelity, functionalized heterocycles.

Basic Information

Product Name	5-Bromo-1-(Phenylsulfonyl)-6-Azaindole-2-Carbaldehyde
CAS No.	1227269-19-3
Molecular Formula	C15H9BrN2O3S
Molecular Weight	377.21 g/mol
Synonyms	5-Bromo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde; 1H-Pyrrolo[2,3-b]pyridine-2-carboxaldehyde, 5-bromo-1-(phenylsulfonyl)-; 5-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde; 5-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxaldehyde; 5-Bromo-1-(phenylsulfonyl)-6-azaindole-2-carboxaldehyde; 5-Bromo-1-(phenylsulfonyl)-6-aza-indole-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-(Phenylsulfonyl)-6-Azaindole-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with the standards expected for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere when appropriate for extended use. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.