Description

1-(Phenylsulfonyl)-2-Chloro-6-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonyl and chloro-substituted azaindole scaffold. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of targeted therapies, particularly within oncology and antiviral drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Probe Synthesis: Employed in creating specialized compounds for investigating biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D pipelines.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Product Name	1-(Phenylsulfonyl)-2-Chloro-6-Azaindole
CAS No.	1227269-16-0
Molecular Formula	C13H9ClN2O2S
Molecular Weight	292.74 g/mol
Synonyms	2-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 2-Chloro-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 2-Chloro-1H-pyrrolo[2,3-b]pyridine 1-(phenylsulfonyl) derivative; 1-Benzenesulfonyl-2-chloro-1H-pyrrolo[2,3-b]pyridine; 2-Chloro-6-azaindole-1-phenylsulfonyl
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-2-Chloro-6-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.