Description

1-(Phenylsulphonyl)-2-Iodo-6-Methyl-5-Nitro-7-Azaindole is a high-purity, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is valued for its unique molecular architecture, which incorporates a reactive iodo group and an electron-withdrawing nitro substituent on an azaindole scaffold, making it a versatile intermediate for constructing complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, catalyst development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science: Acts as a building block for creating specialized organic ligands and functional materials with tailored electronic properties.
• Cross-Coupling Reactions: The aryl iodide moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in novel heterocycle and methodology development.

Basic Information

Product Name	1-(Phenylsulphonyl)-2-Iodo-6-Methyl-5-Nitro-7-Azaindole
CAS No.	1227268-96-3
Molecular Formula	C16H12IN3O4S
Molecular Weight	469.25 g/mol
Synonyms	2-Iodo-6-methyl-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 2-iodo-6-methyl-5-nitro-1-(phenylsulfonyl)-; 2-Iodo-6-methyl-5-nitro-7-azaindole-1-sulfonic acid phenyl ester; 1-(Benzenesulfonyl)-2-iodo-6-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 1-(phenylsulfonyl)-2-iodo-6-methyl-5-nitro-; 1227268-96-3
EINECS	Contact for details

Quality Control

Every batch of 1-(Phenylsulphonyl)-2-Iodo-6-Methyl-5-Nitro-7-Azaindole is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.