Description

5-Bromo-1-(Phenylsulfonyl)-6-Azaindole is a high-value, multi-functional heterocyclic building block designed for advanced organic synthesis. This compound is critical for medicinal chemistry research, serving as a versatile intermediate in the development of novel pharmaceutical candidates. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its modifiable bromo and sulfonyl groups.
• Agrochemical Development: Serves as a precursor in the creation of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing APIs (Active Pharmaceutical Ingredients) and advanced intermediates under cGMP.

Basic Information

Product Name	5-Bromo-1-(Phenylsulfonyl)-6-Azaindole
CAS No.	1227268-88-3
Molecular Formula	C13H9BrN2O2S
Molecular Weight	337.19 g/mol
Synonyms	5-Bromo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-(phenylsulfonyl)-; 5-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1-(phenylsulfonyl)-6-azaindole; 6-Azaindole, 5-bromo-1-(phenylsulfonyl)-; 1227268-88-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-(Phenylsulfonyl)-6-Azaindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by HPLC, NMR, and mass spectrometry. We support development and commercial projects with material suitable for research use and can provide grades aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.