Description

1-(Phenylsulphonyl)-5-Chloro-2-Iodo-7-Azaindole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate complex, halogenated azaindole scaffolds into their molecular libraries.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential kinase inhibitors and other biologically active small molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and hit-to-lead optimization campaigns due to its unique halogenated azaindole core.
• Chemical Biology Probes: Employed in the development of chemical probes for studying enzyme function and cellular signaling pathways.
• Agrochemical Research: Acts as a building block for novel compounds with potential herbicidal or pesticidal activity.
• Material Science: Potential intermediate for creating specialized organic electronic materials or ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules on laboratory to pilot scale.

Basic Information

Product Name	1-(Phenylsulphonyl)-5-Chloro-2-Iodo-7-Azaindole
CAS No.	1227268-73-6
Molecular Formula	C13H8ClIN2O2S
Molecular Weight	418.63 g/mol
Synonyms	5-Chloro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-chloro-2-iodo-1-(phenylsulfonyl)-; 5-Chloro-2-iodo-1-(benzenesulfonyl)-7-azaindole; 1-Benzenesulfonyl-5-chloro-2-iodo-7-azaindole; 7-Azaindole, 1-(phenylsulfonyl)-5-chloro-2-iodo-; 5-Chloro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-5-Chloro-2-Iodo-7-Azaindole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D, and we can support custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.