Description

2-Iodo-4-Azaindole is a high-value, halogenated heterocyclic building block of significant interest in modern organic synthesis and medicinal chemistry. This compound matters as a versatile intermediate that enables the efficient construction of complex molecular architectures, particularly for pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active compounds and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection and pest management.
• Chemical Biology & Probe Development: Serves as a versatile scaffold for creating molecular probes to study biological processes and enzyme functions.
• Material Science: A potential precursor for the synthesis of organic electronic materials and photoactive compounds.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) to introduce the 4-azaindole moiety into more complex systems.
• Library Synthesis for Drug Discovery: Employed in high-throughput and parallel synthesis to generate diverse compound libraries for screening.

Basic Information

Product Name	2-Iodo-4-Azaindole
CAS No.	1227268-72-5
Molecular Formula	C7H5IN2
Molecular Weight	244.03 g/mol
Synonyms	2-Iodo-1H-pyrrolo[3,2-c]pyridine; 2-Iodo-4-azaindole; 1H-Pyrrolo[3,2-c]pyridine, 2-iodo-; 2-Iodo-7-azaindole (common misnomer, correctly 4-azaindole); 2-Iodopyrrolo[3,2-c]pyridine; 4-Azaindole, 2-iodo-; 2-Iodo-4AI
EINECS	Contact for details

Quality Control

Our 2-Iodo-4-Azaindole is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, meeting the exacting standards of research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support regulatory filings, and we can supply material compliant with ICH guidelines for stability and impurity reporting upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.