Description

1-(Phenylsulfonyl)-6-Methoxy-7-Azaindole is a high-purity, advanced pharmaceutical intermediate featuring a sulfonylated azaindole scaffold. This compound is valued for its role as a critical building block in the synthesis of novel, small-molecule drug candidates targeting various therapeutic areas. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development for oncology and kinase-related pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted kinase inhibitors and other bioactive molecules.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Process Chemistry & Scale-Up: Serves as a defined intermediate for route scouting and the development of robust, scalable manufacturing processes under GMP conditions.
• Biochemical Tool Compound: Can be utilized in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Contract Manufacturing: Supplied to CDMOs for the production of clinical trial materials and commercial Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	1-(Phenylsulfonyl)-6-Methoxy-7-Azaindole
CAS No.	1227268-64-5
Molecular Formula	C15H12N2O3S
Molecular Weight	300.33 g/mol
Synonyms	6-Methoxy-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-methoxy-1-(phenylsulfonyl)-; 6-Methoxy-1-(benzenesulfonyl)-7-azaindole; 1-Benzenesulfonyl-6-methoxy-1H-pyrrolo[2,3-b]pyridine; 1-(Phenylsulfonyl)-6-methoxy-1H-pyrrolo[2,3-b]pyridine; 6-Methoxy-1-tosyl-7-azaindole (common misnomer); 7-Azaindole, 6-methoxy-1-(phenylsulfonyl)-
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-6-Methoxy-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.