Description

1-(Phenylsulphonyl)-4-Bromo-7-Azaindole-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of innovative small-molecule drugs, particularly in oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Used in the pilot-scale and commercial-scale manufacturing processes of complex target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	1-(Phenylsulphonyl)-4-Bromo-7-Azaindole-2-Carboxylic Acid
CAS No.	1227268-63-4
Molecular Formula	C16H11BrN2O4S
Molecular Weight	407.24 g/mol
Synonyms	4-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 4-Bromo-1-(benzenesulfonyl)-7-azaindole-2-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 4-bromo-1-(phenylsulfonyl)-; 1-Benzenesulfonyl-4-bromo-7-azaindole-2-carboxylic acid; 4-Bromo-1-(phenylsulfonyl)-7-aza-1H-indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-4-Bromo-7-Azaindole-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.