Description

1-(Phenylsulphonyl)-6-Cyano-4-Chloro-2-Iodo-7-Azaindole is a high-value, multi-functionalized heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for medicinal chemistry research and development, offering a versatile scaffold for the creation of novel pharmaceutical candidates. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other biologically active compounds.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its multiple reactive sites (chloro, iodo, cyano, sulphonyl).
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and cellular pathways.
• Process Chemistry & Scale-Up: Acts as a critical intermediate in the optimization and commercial-scale production of active pharmaceutical ingredients (APIs).
• Material Science Research: Potential building block for the synthesis of organic electronic materials and functional polymers.

Basic Information

Product Name	1-(Phenylsulphonyl)-6-Cyano-4-Chloro-2-Iodo-7-Azaindole
CAS No.	1227268-57-6
Molecular Formula	C14H7ClIN3O2S
Molecular Weight	443.64 g/mol
Synonyms	4-Chloro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile; 7-Azaindole-1-(phenylsulfonyl)-6-carbonitrile-4-chloro-2-iodo derivative; 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile, 4-chloro-2-iodo-1-(phenylsulfonyl)-; 4-Chloro-2-iodo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile; 1-Benzenesulfonyl-4-chloro-2-iodo-6-cyano-7-azaindole
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-6-Cyano-4-Chloro-2-Iodo-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing HPLC purity, NMR, and mass spectrometry data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). This compound may be light-sensitive and moisture-sensitive; handle and store under inert conditions for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.