Description

1-(Phenylsulphonyl)-5-Fluoro-2-Iodo-7-Azaindole is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. Its unique molecular architecture, featuring a 7-azaindole core with strategically placed fluorine, iodine, and phenylsulfonyl substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and exploring novel chemical space.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Potential precursor for organic electronic materials and advanced polymers requiring halogenated heterocycles.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, halogenated indole derivatives.
• Academic & R&D Laboratories: Used in methodological studies for cross-coupling reactions, halogen dance chemistry, and heterocyclic functionalization.

Basic Information

Product Name	1-(Phenylsulphonyl)-5-Fluoro-2-Iodo-7-Azaindole
CAS No.	1227268-55-4
Molecular Formula	C₁₃H₈FIN₂O₂S
Molecular Weight	402.18 g/mol
Synonyms	1-(Benzenesulfonyl)-5-fluoro-2-iodo-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-2-iodo-1-(phenylsulfonyl)-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 5-fluoro-2-iodo-1-(phenylsulfonyl)-; 5-Fluoro-2-iodo-1-tosyl-7-azaindole (common name); 2-Iodo-5-fluoro-1-(phenylsulfonyl)-7-azaindole
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-5-Fluoro-2-Iodo-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.