Description

1-(Phenylsulphonyl)-4-Cyano-2-Iodo-6-Methyl-7-Azaindole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its complex molecular architecture, featuring a 7-azaindole core with distinct sulfonyl, cyano, and iodo substituents, makes it a versatile intermediate for constructing novel pharmacophores and functional materials. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors, where it serves as a critical precursor for the discovery of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and activity-based protein profiling (ABPP) reagents.
• Material Science: Potential precursor for the synthesis of organic semiconductors and advanced functional polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in client-specific, multi-step synthetic routes requiring high-purity, complex intermediates.

Basic Information

Product Name	1-(Phenylsulphonyl)-4-Cyano-2-Iodo-6-Methyl-7-Azaindole
CAS No.	1227268-52-1
Molecular Formula	C16H10IN3O2S
Molecular Weight	435.24 g/mol
Synonyms	1-(Phenylsulfonyl)-4-cyano-2-iodo-6-methyl-1H-pyrrolo[2,3-b]pyridine; 4-Cyano-2-iodo-6-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 2-Iodo-6-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 7-Azaindole, 1-(phenylsulfonyl)-4-cyano-2-iodo-6-methyl-; 1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile, 2-iodo-6-methyl-1-(phenylsulfonyl)-
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-4-Cyano-2-Iodo-6-Methyl-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.