Description

1-(Phenylsulphonyl)-4-Cyano-2-Methyl-7-Azaindole is a high-value, advanced pharmaceutical intermediate with the CAS registry number 1227268-51-0. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on creating novel therapeutic agents, particularly in oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Biology Probes: Serves as a precursor for developing selective chemical probes to study enzyme function and signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for exploratory research in heterocyclic and organic chemistry.

Basic Information

Product Name	1-(Phenylsulphonyl)-4-Cyano-2-Methyl-7-Azaindole
CAS No.	1227268-51-0
Molecular Formula	C17H11N3O2S
Molecular Weight	321.36 g/mol
Synonyms	1-(Phenylsulfonyl)-4-cyano-2-methyl-1H-pyrrolo[2,3-b]pyridine; 4-Cyano-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-cyano-2-methyl-1-(phenylsulfonyl)-; 1-(Benzenesulfonyl)-4-cyano-2-methyl-7-azaindole; 4-Cyano-2-methyl-1-(phenylsulfonyl)-7-azaindole; 7-Azaindole, 1-(phenylsulfonyl)-4-cyano-2-methyl-
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-4-Cyano-2-Methyl-7-Azaindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and commercial projects with material that meets stringent internal specifications, suitable for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.