Description

1-(Phenylsulphonyl)-6-Cyano-2-Iodo-7-Azaindole is a high-purity, multi-functional heterocyclic building block designed for advanced research and development. This compound is valued for its unique molecular architecture, which incorporates key functional groups—sulfonyl, cyano, and iodo—making it a versatile intermediate for constructing complex molecules. It is primarily sought after by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry, including the synthesis of kinase inhibitors and other biologically active compounds. Our supply ensures consistent quality and reliable availability for critical discovery and process development projects.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for various disease targets.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the design and synthesis of potent and selective kinase inhibitors.
• Agrochemical Synthesis: Employed in the research and development of new active ingredients for crop protection.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis services requiring complex functionalization.

Basic Information

Product Name	1-(Phenylsulphonyl)-6-Cyano-2-Iodo-7-Azaindole
CAS No.	1227267-29-9
Molecular Formula	C14H8IN3O2S
Molecular Weight	409.20 g/mol
Synonyms	1-(Benzenesulfonyl)-6-cyano-2-iodo-1H-pyrrolo[2,3-b]pyridine; 2-Iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile; 6-Cyano-2-iodo-1-(phenylsulfonyl)-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile, 2-iodo-1-[(phenylsulfonyl)]-; 1-(Phenylsulfonyl)-2-iodo-6-cyano-7-azaindole; 2-Iodo-6-cyano-1-(phenylsulfonyl)-7-azaindole
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-6-Cyano-2-Iodo-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with the standards required for research and development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.