Description

1-(Phenylsulphonyl)-6-Chloro-2-Iodo-7-Azaindole is a high-purity, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is valued for its unique molecular scaffold, which incorporates halogen and sulfonyl functional groups, making it a versatile intermediate for constructing complex pharmacophores. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery, lead optimization, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Chemical Biology: Serves as a probe or a tagged molecule in the study of protein-ligand interactions and biological target identification.
• Material Science: Potential precursor for the development of organic electronic materials and specialty polymers.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring complex indole derivatives.
• Academic Research: Used in university and institutional labs for methodological development in cross-coupling and heterocyclic chemistry.

Basic Information

Product Name	1-(Phenylsulphonyl)-6-Chloro-2-Iodo-7-Azaindole
CAS No.	1227267-22-2
Molecular Formula	C13H7ClIN2O2S
Molecular Weight	417.62 g/mol
Synonyms	6-Chloro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-2-iodo-1-(phenylsulfonyl)-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 6-chloro-2-iodo-1-(phenylsulfonyl)-; 1-Benzenesulfonyl-6-chloro-2-iodo-7-azaindole; 6-Chloro-2-iodo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Phenylsulfonyl)-6-chloro-2-iodo-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 6-chloro-2-iodo-1-(phenylsulfonyl)-
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-6-Chloro-2-Iodo-7-Azaindole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.